منابع مشابه
Designer Drug Detective Work
O n an unseasonably warm spring morning in his office in Baltimore, neurochemist Michael H. Baumann eagerly flipped through a spreadsheet. It listed hundreds of chemical names of suspected drugs seized by local, state, and federal law enforcement agencies over the past three years. " When police bust people with some white powder or a baggie full of pot-looking material, it gets sent to forensi...
متن کاملDrug Dosage Formulations
The discovery and development of a new drug can be a lengthy and expensive business (Fig. 1). The starting point is the active compound as synthesized by the medicinal chemist and screened by the pharmacologist. There then follows a series of complex tests and evaluations to produce a satisfactory formulation and sufficient data for presentation to regulatory authorities such as the Committee o...
متن کاملin translation: translators on their work and what it means
کتاب در باب ترجمه، اثر استر آلن و سوزان برنوفسکی منتشر شده در ماه می 2013 توسط نشریه کلمبیا است. نویسندگان در این کتاب به بررسی 18 مترجم با در نظر گرفتن نقش آثاری که این مترجمان ترجمه کرده اند میپردازند. کتاب به دو بخش تقسیم میشود: " مترجم در جهان" و " کار مترجم" این دو بخش مقالات همیشگی ترجمه و موقعیت خاص ادبیات بیگانه در جهان وسیع امروزی را مورد خطاب قرار میدهد. در این کتاب مقالات متعددی از ن...
Drug dosage individualization based on a random-effects linear model.
This article investigates drug dosage individualization when the patient population can be described with a random-effects linear model of a continuous pharmacokinetic or pharmacodynamic response. Specifically, we show through both decision-theoretic arguments and simulations that a published clinical algorithm may produce better individualized dosages than some traditional methods of therapeut...
متن کاملComputerized advice on drug dosage to improve prescribing practice.
BACKGROUND Maintaining therapeutic concentrations of drugs with a narrow therapeutic window is a complex task. Several computer systems have been designed to help doctors determine optimum drug dosage. Significant improvements in health care could be achieved if computer advice improved health outcomes and could be implemented in routine practice in a cost-effective fashion. This is an updated v...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature
سال: 2014
ISSN: 0028-0836,1476-4687
DOI: 10.1038/505165a